Predicted to enable transcription coactivator activity. Predicted to be involved in positive regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Predicted to be part of mediator complex. Expressed in several structures, including TL.a; TL.p; TR.a; TR.p; and seam cell. Human ortholog(s) of this gene implicated in autosomal dominant intellectual developmental disorder and dextro-looped transposition of the great arteries. Is an ortholog of human MED13 (mediator complex subunit 13) and MED13L (mediator complex subunit 13L).
Involved in lateral inhibition; positive regulation of Notch signaling pathway; and regulation of cell fate specification. Predicted to be located in nucleus. Predicted to be part of mediator complex. Expressed in body wall musculature.
Is affected by several genes including mdt-15; met-2; and spr-5 based on RNA-seq and microarray studies. Is affected by paraquat based on RNA-seq studies.
Is affected by several genes including sir-2.1; mdt-15; and drh-3 based on tiling array; microarray; and RNA-seq studies. Is affected by dibromoacetic acid based on microarray studies.