- acs-13 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable long-chain fatty acid-CoA ligase activity. Predicted to be involved in long-chain fatty acid metabolic process. Predicted to be located in endoplasmic reticulum and membrane. Expressed in head. Human ortholog(s) of this gene implicated in acute myeloid leukemia; congenital diarrhea; and obesity. Is an ortholog of human ACSL1 (acyl-CoA synthetase long chain family member 1); ACSL5 (acyl-CoA synthetase long chain family member 5); and ACSL6 (acyl-CoA synthetase long chain family member 6).
- acs-15 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable long-chain fatty acid-CoA ligase activity. Predicted to be involved in long-chain fatty acid metabolic process. Predicted to be located in endoplasmic reticulum and membrane. Human ortholog(s) of this gene implicated in acute myeloid leukemia and obesity. Is an ortholog of human ACSL1 (acyl-CoA synthetase long chain family member 1) and ACSL6 (acyl-CoA synthetase long chain family member 6).
- acs-18 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable long-chain fatty acid-CoA ligase activity. Predicted to be involved in long-chain fatty acid metabolic process. Predicted to be located in endoplasmic reticulum and membrane. Human ortholog(s) of this gene implicated in acute myeloid leukemia and obesity. Is an ortholog of human ACSL1 (acyl-CoA synthetase long chain family member 1) and ACSL6 (acyl-CoA synthetase long chain family member 6).
- acs-17 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable long-chain fatty acid-CoA ligase activity. Predicted to be involved in long-chain fatty acid metabolic process; long-chain fatty-acyl-CoA metabolic process; and neuron differentiation. Predicted to be located in endoplasmic reticulum; lipid droplet; and plasma membrane. Human ortholog(s) of this gene implicated in several diseases, including lung cancer; non-syndromic X-linked intellectual disability 63; and prostate cancer. Is an ortholog of human ACSL3 (acyl-CoA synthetase long chain family member 3) and ACSL4 (acyl-CoA synthetase long chain family member 4).
- acs-4 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable long-chain fatty acid-CoA ligase activity. Predicted to be involved in long-chain fatty acid metabolic process; long-chain fatty-acyl-CoA metabolic process; and neuron differentiation. Located in lipid droplet. Expressed in hypodermis; intestine; pharynx; and somatic nervous system. Human ortholog(s) of this gene implicated in several diseases, including lung cancer; non-syndromic X-linked intellectual disability 63; and prostate cancer. Is an ortholog of human ACSL3 (acyl-CoA synthetase long chain family member 3) and ACSL4 (acyl-CoA synthetase long chain family member 4).
- acdh-12 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable fatty-acyl-CoA binding activity and very-long-chain-acyl-CoA dehydrogenase activity. Human ortholog(s) of this gene implicated in Alzheimer's disease and very long chain acyl-CoA dehydrogenase deficiency. Is an ortholog of human ACADVL (acyl-CoA dehydrogenase very long chain).
- acs-5 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable long-chain fatty acid-CoA ligase activity. Predicted to be involved in long-chain fatty acid metabolic process. Predicted to be located in endoplasmic reticulum and membrane. Expressed in hypodermis. Human ortholog(s) of this gene implicated in congenital diarrhea. Is an ortholog of human ACSL5 (acyl-CoA synthetase long chain family member 5).
- acs-3 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable long-chain fatty acid-CoA ligase activity. Predicted to be involved in long-chain fatty acid metabolic process. Predicted to be located in endoplasmic reticulum and membrane. Expressed in several structures, including excretory cell; intestine; seam cell; tail; and vulva.
- pmp-5 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable ATP binding activity; ATPase-coupled transmembrane transporter activity; and long-chain fatty acid transporter activity. Predicted to be involved in fatty acid catabolic process; long-chain fatty acid import into peroxisome; and peroxisome organization. Predicted to be located in peroxisomal membrane. Is an ortholog of human ABCD4 (ATP binding cassette subfamily D member 4).
- SEI1 [Search on AGR]
Saccharomyces cerevisiae Seipin involved in lipid droplet (LD) assembly; controls lipid particle morphology, number, and size; promotes initiation of LD formation on the ER; ensures that LDs bud from the ER towards the cytosolic side of the membrane; forms a complex with Ldb16p at ER-LD contact sites, stabilizing these sites; null mutants have localized accumulation of phosphatidic acid (PA) marker proteins; BSCL2, human homolog implicated in congenital lipodystrophy, complements yeast null mutant