- ZFPM2-AS1 [Search on AGR]
Homo sapiens ASSOCIATED WITH 46,XY sex reversal 3; 46,XY sex reversal 9; Diaphragmatic Hernia 3; INTERACTS WITH aristolochic acid A; Didecyldimethylammonium; methylparaben
- Akr1c13 [Search on AGR]
Rattus norvegicus Human ortholog(s) of this gene implicated in 46,XY sex reversal 8. Orthologous to human AKR1C4 (aldo-keto reductase family 1 member C4).
- Rsxr [Search on AGR]
Mus musculus PHENOTYPE: The Rsxr<sup>129S1/Sv</sup> allele confers resistance to sex reversal in genetic XY males from consomic line B6.129-Chr Y<sup>POS</sup>. The Rsxr<sup>C57BL/6J</sup> allele confers sex reversal in genetic XY males from consomic line C57BL/6J-Hba<sup>th-J</sup> Chr Y<sup>POS</sup>. [provided by MGI curators]
- Akr1c12 [Search on AGR]
Rattus norvegicus Human ortholog(s) of this gene implicated in 46,XY sex reversal 8. Orthologous to human AKR1C4 (aldo-keto reductase family 1 member C4).
- Akr1c19 [Search on AGR]
Rattus norvegicus Human ortholog(s) of this gene implicated in 46,XY sex reversal 8. Orthologous to human AKR1C4 (aldo-keto reductase family 1 member C4).
- Pbx4 [Search on AGR]
Rattus norvegicus Predicted to enable sequence-specific DNA binding activity. Predicted to be located in XY body. Orthologous to human PBX4 (PBX homeobox 4); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; acetamide; all-trans-retinoic acid.
- t [Search on AGR]
Mus musculus PHENOTYPE: Homozygous mice die during embryonic development. Heterozygous mice have skeletal abnormalities. On specific genetic backgrounds, some alleles cause partial or complete sex-reversal of chromosomally XY mice. [provided by MGI curators]
- Sry [Search on AGR]
Mus musculus PHENOTYPE: Variations in expression of alleles on specific backgrounds result in partial and/or complete male to female sex reversal. Deletion of alleles results in XY females. [provided by MGI curators]
- Sry [Search on AGR]
Rattus norvegicus Enables enzyme binding activity and sequence-specific DNA binding activity. Involved in male sex determination and positive regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Predicted to be part of transcription regulator complex. Human ortholog(s) of this gene implicated in 46,XX sex reversal 1; 46,XY sex reversal; and 46,XY sex reversal 1. Orthologous to human SRY (sex determining region Y); INTERACTS WITH ammonium chloride; bisphenol A; copper atom.
- Dhh [Search on AGR]
Rattus norvegicus Predicted to enable calcium ion binding activity; patched binding activity; and zinc ion binding activity. Involved in several processes, including response to estradiol; response to estrogen; and spermatid development. Predicted to be located in plasma membrane. Human ortholog(s) of this gene implicated in 46,XY sex reversal and 46,XY sex reversal 7. Orthologous to human DHH (desert hedgehog signaling molecule); PARTICIPATES IN altered Hedgehog signaling pathway; Hedgehog signaling pathway; INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2,3-bis(4-hydroxyphenyl)propionitrile.