Is affected by several genes including eat-2; prg-1; and alg-1 based on RNA-seq studies. Is affected by multi-walled carbon nanotube based on RNA-seq studies. Used to study Parkinson's disease.
Enables ornithine decarboxylase activity. Involved in putrescine biosynthetic process from ornithine. Predicted to be located in cytoplasm. Expressed in intestine and male gonad. Human ortholog(s) of this gene implicated in esophagus squamous cell carcinoma; hepatocellular carcinoma; and liver cirrhosis. Is an ortholog of human AZIN1 (antizyme inhibitor 1); AZIN2 (antizyme inhibitor 2); and ODC1 (ornithine decarboxylase 1).
Expressed in egg-laying apparatus; intestine; neurons; and pharynx. Is predicted to encode a protein with the following domains: Uncharacterized strongylid L4 protein; Uncharacterized Strongylid L4 protein; and Phosphorylation site.
Enables high-affinity sodium:dicarboxylate symporter activity and succinate transmembrane transporter activity. Involved in determination of adult lifespan and succinate transport. Predicted to be located in membrane. Expressed in alimentary system. Is an ortholog of human SLC13A2 (solute carrier family 13 member 2).
Predicted to enable long-chain fatty acyl-CoA binding activity. Involved in determination of adult lifespan and lipid storage. Is an ortholog of human DBI (diazepam binding inhibitor, acyl-CoA binding protein).