rpoa-49

Caenorhabditis elegans

Predicted to enable DNA binding activity. Predicted to be involved in RNA polymerase I preinitiation complex assembly; nucleolar large rRNA transcription by RNA polymerase I; and transcription elongation from RNA polymerase I promoter. Predicted to be located in nucleolus. Predicted to be part of RNA polymerase I complex. Is an ortholog of human POLR1E (RNA polymerase I subunit E).

tif-1A

Caenorhabditis elegans

Predicted to enable RNA polymerase I core binding activity and RNA polymerase I general transcription initiation factor activity. Predicted to be involved in transcription initiation from RNA polymerase I promoter. Predicted to be located in nucleus. Is an ortholog of human RRN3 (RRN3 homolog, RNA polymerase I transcription factor).

F23H11.2

Caenorhabditis elegans

Predicted to enable RNA polymerase I core promoter sequence-specific DNA binding activity. Predicted to be involved in RNA polymerase I preinitiation complex assembly and nucleolar large rRNA transcription by RNA polymerase I. Predicted to be located in nucleolus. Predicted to be part of RNA polymerase I core factor complex and RNA polymerase transcription factor SL1 complex.

Y54F10AM.5

Caenorhabditis elegans

Predicted to be involved in mitochondrial respiratory chain complex I assembly. Predicted to be located in mitochondrial inner membrane and respirasome. Predicted to be part of mitochondrial respiratory chain complex I. Human ortholog(s) of this gene implicated in nuclear type mitochondrial complex I deficiency. Is an ortholog of human NDUFA8 (NADH:ubiquinone oxidoreductase subunit A8).

Y39A1A.9

Caenorhabditis elegans

Predicted to be involved in female meiosis I; mRNA stabilization; and male meiosis I. Predicted to be located in cytoplasm and nucleus. Is an ortholog of human MEIOC (meiosis specific with coiled-coil domain).

rpac-40

Caenorhabditis elegans

Predicted to enable protein dimerization activity. Predicted to contribute to RNA polymerase I activity and RNA polymerase III activity. Predicted to be involved in transcription by RNA polymerase I and transcription by RNA polymerase III. Predicted to be part of RNA polymerase I complex and RNA polymerase III complex. Human ortholog(s) of this gene implicated in Treacher Collins syndrome 3 and hypomyelinating leukodystrophy 11. Is an ortholog of human POLR1C (RNA polymerase I and III subunit C).

oig-3

Caenorhabditis elegans

Expressed in PVT; gonad; gonadal sheath cell; and pharynx. Is predicted to encode a protein with the following domains: Phosphorylation site; Immunoglobulin I-set domain; Immunoglobulin I-set; Immunoglobulin-like fold; and Immunoglobulin-like domain superfamily.

nduf-9

Caenorhabditis elegans

Predicted to be involved in mitochondrial respiratory chain complex I assembly and ubiquinone-6 biosynthetic process. Predicted to be located in mitochondrion. Predicted to be part of mitochondrial respiratory chain complex I. Expressed in head and tail. Human ortholog(s) of this gene implicated in nuclear type mitochondrial complex I deficiency 26. Is an ortholog of human NDUFA9 (NADH:ubiquinone oxidoreductase subunit A9).

rpoa-12

Caenorhabditis elegans

Predicted to enable nucleic acid binding activity and zinc ion binding activity. Predicted to contribute to DNA-directed 5'-3' RNA polymerase activity. Predicted to be involved in termination of RNA polymerase I transcription. Predicted to be located in nucleolus. Predicted to be part of RNA polymerase I complex. Is an ortholog of human POLR1H (RNA polymerase I subunit H).

C18E9.4

Caenorhabditis elegans

Predicted to be involved in mitochondrial respiratory chain complex I assembly. Predicted to be located in mitochondrial inner membrane and respirasome. Predicted to be integral component of membrane. Predicted to be part of mitochondrial respiratory chain complex I. Human ortholog(s) of this gene implicated in Alzheimer's disease and nuclear type mitochondrial complex I deficiency 25. Is an ortholog of human NDUFB3 (NADH:ubiquinone oxidoreductase subunit B3).