dop-2 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Enables dopamine neurotransmitter receptor activity, coupled via Gi/Go. Involved in several processes, including cellular response to organonitrogen compound; male mating behavior; and regulation of locomotion involved in locomotory behavior. Predicted to be located in dendrite. Expressed in GLR; male-specific anatomical entity; and neurons. Used to study Parkinson's disease and nicotine dependence. Human ortholog(s) of this gene implicated in several diseases, including Alzheimer's disease; end stage renal disease; essential tremor 1; and type 2 diabetes mellitus. Is an ortholog of human DRD3 (dopamine receptor D3).