mek-1 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Enables JUN kinase kinase activity and SH2 domain binding activity. Involved in several processes, including gamete generation; response to metal ion; and stress-activated MAPK cascade. Predicted to be located in cytoplasm. Expressed in several structures, including ganglia; hermaphrodite gonad; intestine; nerve ring; and pharynx. Human ortholog(s) of this gene implicated in colon adenocarcinoma; lung adenocarcinoma; and prostate carcinoma in situ. Is an ortholog of human MAP2K7 (mitogen-activated protein kinase kinase 7).