Npvf [Search on AGR]
Rattus norvegicus Enables signaling receptor binding activity. Involved in neuropeptide signaling pathway. Predicted to be located in extracellular region. Orthologous to human NPVF (neuropeptide VF precursor); INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; ammonium chloride.
Fv5 [Search on AGR]
Mus musculus PHENOTYPE: Alleles at this locus determine response to Friend Virus-P (VF-P) infection. DBA/2, BALB/c and AKR (p allele) show early polycythemia (high hematocrit); CBA/J and C3H (a allele) show early anemic response (low hematocrit). Heterozygotes have slight polycythemia with intermediate hematocrits. [provided by MGI curators]
Rnf216 [Search on AGR]
Rattus norvegicus Predicted to enable ubiquitin protein ligase activity. Involved in protein catabolic process, modulating synaptic transmission and regulation of postsynaptic neurotransmitter receptor internalization. Is active in several cellular components, including Schaffer collateral - CA1 synapse; glutamatergic synapse; and postsynaptic endocytic zone. Human ortholog(s) of this gene implicated in Gordon Holmes syndrome. Orthologous to human RNF216 (ring finger protein 216); INTERACTS WITH acrylamide; bisphenol A; cyclophosphamide.