klf-1 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Enables RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in several processes, including apoptotic cell clearance; regulation of transcription by RNA polymerase II; and xenobiotic metabolic process. Acts upstream of or within determination of adult lifespan. Part of chromatin. Expressed in hypodermis; intestine; and neurons. Human ortholog(s) of this gene implicated in prostate cancer and stomach cancer. Is an ortholog of human KLF6 (KLF transcription factor 6).