shc-1 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Enables insulin-like growth factor receptor binding activity; mitogen-activated protein kinase kinase binding activity; and mitogen-activated protein kinase kinase kinase binding activity. Involved in positive regulation of axon regeneration; response to endoplasmic reticulum stress; and response to metal ion. Located in cytoplasm and nucleus. Expressed in gonad; head; neurons; and tail. Human ortholog(s) of this gene implicated in fatty liver disease. Is an ortholog of human SHC4 (SHC adaptor protein 4).