csb-1 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable ATP-dependent activity, acting on DNA and DNA binding activity. Involved in UV protection and transcription-coupled nucleotide-excision repair. Predicted to be located in nucleus. Expressed in several structures, including copulatory spicule; egg-laying apparatus; neurons; oocyte; and postcloacal sensillum. Used to study Cockayne syndrome. Human ortholog(s) of this gene implicated in several diseases, including Cockayne syndrome (multiple); gastrointestinal system cancer (multiple); and respiratory system cancer (multiple). Is an ortholog of human ERCC6 (ERCC excision repair 6, chromatin remodeling factor).