mom-4 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Enables MAP kinase kinase kinase activity. Involved in several processes, including cell fate commitment; embryonic digestive tract morphogenesis; and signal transduction. Located in striated muscle dense body. Expressed in BAGL and BAGR. Human ortholog(s) of this gene implicated in several diseases, including artery disease (multiple); frontometaphyseal dysplasia 2; and intrinsic cardiomyopathy (multiple). Is an ortholog of human MAP3K7 (mitogen-activated protein kinase kinase kinase 7).