ftt-2 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Enables DNA-binding transcription factor binding activity. Involved in cytoplasmic sequestering of protein; dauer larval development; and negative regulation of protein import into nucleus. Located in cytoplasm and nucleus. Expressed in several structures, including C; E; Psub3; gonad; and intestine. Human ortholog(s) of this gene implicated in several diseases, including carcinoma (multiple); ovarian cancer; and urinary bladder cancer. Is an ortholog of human YWHAB (tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein beta) and YWHAZ (tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta).