tdp-1 [Browse genome (BioProject PRJNA13758)] [Legacy GBrowse]
Is an ortholog of human TARDBP (TAR DNA binding protein). Exhibits single-stranded RNA binding activity. Is involved in several processes, including determination of adult lifespan; hyperosmotic response; and response to oxidative stress. Localizes to nucleus. Is expressed in several structures, including body wall musculature; intestine; muscle cell; neurons; and pharynx. Is used to study amyotrophic lateral sclerosis. Human ortholog(s) of this gene are implicated in amyotrophic lateral sclerosis type 10.