Enriched in anterior hypodermis; dopaminergic neurons; head neurons; interfacial epithelial cell; and intestine based on Chronogram; tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including
daf-2;
daf-12; and
rrf-3 based on microarray; tiling array; and RNA-seq studies. Is affected by sixteen chemicals including hydrogen sulfide; D-glucose; and stavudine based on microarray and RNA-seq studies. Human ortholog(s) of this gene implicated in malaria. Human CR1 enables complement receptor activity and opsonin binding activity. Is predicted to encode a protein with the following domains: Sushi repeat (SCR repeat); Sushi/SCR/CCP domain; and Sushi/SCR/CCP superfamily. Is an ortholog of human CR1 (complement C3b/C4b receptor 1 (Knops blood group)).