evl-18 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable DNA replication origin binding activity; chromatin binding activity; and single-stranded DNA binding activity. Predicted to be involved in DNA replication initiation; double-strand break repair via break-induced replication; and mitotic DNA replication preinitiation complex assembly. Located in nucleus. Used to study chromosome 22q11.2 deletion syndrome, distal. Human ortholog(s) of this gene implicated in Meier-Gorlin syndrome 7. Is an ortholog of human CDC45 (cell division cycle 45).