scc-3 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable DNA binding activity and chromatin binding activity. Involved in organelle organization and regulation of DNA damage checkpoint. Located in condensed chromosome. Part of chromatin and cohesin complex. Expressed in gonad. Human ortholog(s) of this gene implicated in several diseases, including intellectual disability (multiple); primary ovarian insufficiency 8; and spermatogenic failure 61. Is an ortholog of human STAG1 (STAG1 cohesin complex component) and STAG2 (STAG2 cohesin complex component).