lmn-1 [Browse genome (BioProject PRJNA13758)] [Legacy GBrowse]
Is an ortholog of human LMNA (lamin A/C). Exhibits histone binding activity; identical protein binding activity; and structural molecule activity. Is involved in several processes, including determination of adult lifespan; nuclear migration along microtubule; and nuclear pore distribution. Localizes to nuclear envelope and nuclear periphery. Is expressed in several structures, including ventral cord blast cell. Is used to study Emery-Dreifuss muscular dystrophy; congenital muscular dystrophy; and progeria. Human ortholog(s) of this gene are implicated in several diseases, including Charcot-Marie-Tooth disease (multiple); epidermolysis bullosa simplex (multiple); and myopathy (multiple).