Predicted to enable ubiquitin protein ligase activity. Predicted to be involved in protein ubiquitination and ubiquitin-dependent protein catabolic process. Located in nucleus. Expressed in several structures, including body wall musculature; hermaphrodite distal tip cell; intestine; pharynx; and vulval precursor cell. Human ortholog(s) of this gene implicated in esophagus squamous cell carcinoma and nasopharynx carcinoma. Is an ortholog of human SPEN (spen family transcriptional repressor).
Predicted to enable RNA binding activity. Located in nucleus. Expressed in epithelial cell; lateral ganglion; muscle cell; and neurons. Is an ortholog of human RBM15 (RNA binding motif protein 15) and RBM15B (RNA binding motif protein 15B).
Is predicted to encode a protein with the following domains: Spen paralogue and orthologue SPOC, C-terminal; SPOC-like, C-terminal domain superfamily; and SPOC domain. Is an ortholog of C. elegans din-1 and nono-1.
Is predicted to encode a protein with the following domains: Spen paralogue and orthologue SPOC, C-terminal; SPOC-like, C-terminal domain superfamily; and SPOC domain. Is an ortholog of C. elegans din-1 and nono-1.