- ND-42 [Search on AGR]
Drosophila melanogaster NADH dehydrogenase (ubiquinone) 42 kDa subunit (ND-42) encodes an ortholog of human NDUFA10, a subunit of complex I of the mitochondrial electron transport chain (NADH:ubiquinone reductase). ND-42 acts genetically as a suppressor of some Pink1 phenotypes.
- ND-39 [Search on AGR]
Drosophila melanogaster NADH dehydrogenase (ubiquinone) 39 kDa subunit (ND-39) encodes a subunit of mitochondrial respiratory complex I (cI, NADH:ubiquinone oxidoreductase).
- ND-SGDH [Search on AGR]
Drosophila melanogaster NADH dehydrogenase (ubiquinone) SGDH subunit (ND-SGDH) encodes a protein required for proper mitochondrial electron transport chain function. It is involved in longevity and redox response.
- ND-20 [Search on AGR]
Drosophila melanogaster NADH dehydrogenase (ubiquinone) 20 kDa subunit (ND-20) encodes a component of the mitochondrial electron transport chain and is involved in determination of life span.
- Ndp [Search on AGR]
Mus musculus PHENOTYPE: Male mice in which this X-linked gene has been inactivated exhibit retinopathy similar to that observed in patients with Norrie Disease (ND). [provided by MGI curators]
- ND-20L [Search on AGR]
Drosophila melanogaster NADH dehydrogenase (ubiquinone) 20 kDa subunit-like (ND-20L) encodes a flavoprotein and iron-sulfur-containing oxidoreductase that catalyzes the oxidation of NADH to NAD. It is a component of the mitochondrial electron transport complex I, which is part of the oxidative phosphorylation pathway. It may have a role in regulating aggression behavior.
- ND-51 [Search on AGR]
Drosophila melanogaster NADH dehydrogenase (ubiquinone) 51 kDa subunit (ND-51) encodes a flavoprotein and iron-sulfur-containing oxidoreductase that catalyzes the oxidation of NADH to NAD. It is a component of the mitochondrial electron transport complex I, which is part of the oxidative phosphorylation pathway. It may have a role in regulating aggression behavior.
- Coq3 [Search on AGR]
Homo sapiens Ubiquinone, also known as coenzyme Q, or Q, is a critical component of the electron transport pathways of both eukaryotes and prokaryotes (Jonassen and Clarke, 2000 [PubMed 10777520]). This lipid consists of a hydrophobic isoprenoid tail and a quinone head group. The tail varies in length depending on the organism, but its purpose is to anchor coenzyme Q to the membrane. The quinone head group is responsible for the activity of coenzyme Q in the respiratory chain. The S. cerevisiae COQ3 gene encodes an O-methyltransferase required for 2 steps in the biosynthetic pathway of coenzyme Q. This enzyme methylates an early coenzyme Q intermediate, 3,4-dihydroxy-5-polyprenylbenzoic acid, as well as the final intermediate in the pathway, converting demethyl-ubiquinone to coenzyme Q. The COQ3 gene product is also capable of methylating the distinct prokaryotic early intermediate 2-hydroxy-6-polyprenyl phenol.[supplied by OMIM, Mar 2008]