- end-1 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Enables DNA-binding transcription activator activity, RNA polymerase II-specific. Involved in endodermal cell fate specification and positive regulation of transcription by RNA polymerase II. Located in nucleus. Expressed in E; E lineage cell; Ea; and Ep.
- end-3 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in endodermal cell fate specification and mesodermal cell fate specification. Located in nucleus. Expressed in E; E lineage cell; Ea; Ep; and intestine.
- med-1 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Enables sequence-specific DNA binding activity. Involved in endodermal cell fate specification and pharynx development. Located in nucleus. Expressed in several structures, including MSaaaap; MSaapap; MSappp; MSppapa; and MSppapp.
- T08D2.8 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable microtubule plus end polymerase and microtubule plus-end binding activity. Predicted to be involved in establishment or maintenance of microtubule cytoskeleton polarity; microtubule polymerization; and spindle organization. Predicted to be located in intracellular non-membrane-bounded organelle and supramolecular complex.
- cpf-1 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to be involved in mRNA 3'-end processing. Predicted to be located in nucleus. Predicted to be part of mRNA cleavage stimulating factor complex. Is an ortholog of human CSTF1 (cleavage stimulation factor subunit 1).
- ptrn-1 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Enables microtubule minus-end binding activity. Involved in cytoplasmic microtubule organization and nematode larval development. Located in microtubule minus-end. Expressed in hypodermis; intestine; nervous system; and pharynx. Human ortholog(s) of this gene implicated in complex cortical dysplasia with other brain malformations. Is an ortholog of human CAMSAP1 (calmodulin regulated spectrin associated protein 1); CAMSAP2 (calmodulin regulated spectrin associated protein family member 2); and CAMSAP3 (calmodulin regulated spectrin associated protein family member 3).
- dli-1 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable dynein heavy chain binding activity. Involved in regulation of dendrite morphogenesis and retrograde axonal transport. Located in microtubule plus-end and neuron projection. Expressed in ciliated neurons; hypodermis; and pharynx. Is an ortholog of human DYNC1LI2 (dynein cytoplasmic 1 light intermediate chain 2).
- ints-1 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to be involved in U2 snRNA 3'-end processing. Predicted to be part of integrator complex. Human ortholog(s) of this gene implicated in neurodevelopmental disorder with cataracts, poor growth, and dysmorphic facies. Is an ortholog of human INTS1 (integrator complex subunit 1).