pgp-4 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable ATPase-coupled transmembrane transporter activity and efflux transmembrane transporter activity. Involved in regulatory ncRNA-mediated post-transcriptional gene silencing and stress response to cadmium ion. Predicted to be located in plasma membrane. Expressed in excretory canal. Human ortholog(s) of this gene implicated in several diseases, including autoimmune disease (multiple); carcinoma (multiple); and intrahepatic cholestasis (multiple). Is an ortholog of several human genes including ABCB1 (ATP binding cassette subfamily B member 1); ABCB11 (ATP binding cassette subfamily B member 11); and ABCB4 (ATP binding cassette subfamily B member 4).