mec-12 [Browse genome (BioProject PRJNA13758)] [Legacy GBrowse] [Search on AGR]
Predicted to enable GTP binding activity. Predicted to be a structural constituent of cytoskeleton. Involved in several processes, including positive regulation of detection of mechanical stimulus involved in sensory perception of touch; positive regulation of mechanosensory behavior; and response to mechanical stimulus. Located in axon; microtubule; and neuronal cell body. Expressed in nerve ring and neurons. Human ortholog(s) of this gene implicated in several diseases, including Down syndrome; amyotrophic lateral sclerosis type 22; and lissencephaly 3. Is an ortholog of human TUBA1A (tubulin alpha 1a); TUBA1B (tubulin alpha 1b); and TUBA3D (tubulin alpha 3d).