ced-5 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Enables SH3 domain binding activity and enzyme binding activity. Involved in several processes, including left/right axis specification; positive regulation of distal tip cell migration; and vesicle-mediated transport. Located in presynapse. Part of guanyl-nucleotide exchange factor complex. Expressed in body wall muscle cell; hermaphrodite somatic gonadal cell; and intestinal cell. Human ortholog(s) of this gene implicated in attention deficit hyperactivity disorder and immunodeficiency 40. Is an ortholog of human DOCK2 (dedicator of cytokinesis 2) and DOCK5 (dedicator of cytokinesis 5).