pmk-1 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Enables MAP kinase activity and RNA polymerase II-specific DNA-binding transcription factor binding activity. Involved in several processes, including defense response to other organism; positive regulation of macromolecule biosynthetic process; and response to inorganic substance. Located in cytosol and nucleus. Expressed in several structures, including germ line; head neurons; intestine; and vulval precursor cell. Used to study Parkinson's disease. Human ortholog(s) of this gene implicated in gastrointestinal system cancer (multiple). Is an ortholog of human MAPK11 (mitogen-activated protein kinase 11) and MAPK14 (mitogen-activated protein kinase 14).