swsn-1 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Enables identical protein binding activity. Involved in several processes, including determination of adult lifespan; negative regulation of vulval development; and positive regulation of growth rate. Predicted to be part of SWI/SNF complex. Expressed in several structures, including vulval cell. Used to study alcohol use disorder and cancer. Human ortholog(s) of this gene implicated in Coffin-Siris syndrome 8; carcinoma (multiple); and hydrocephalus. Is an ortholog of human SMARCC1 (SWI/SNF related, matrix associated, actin dependent regulator of chromatin subfamily c member 1) and SMARCC2 (SWI/SNF related, matrix associated, actin dependent regulator of chromatin subfamily c member 2).