hsp-90 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Enables several functions, including ATP hydrolysis activity; nuclear glucocorticoid receptor binding activity; and protein phosphatase 5 binding activity. Involved in several processes, including determination of adult lifespan; protein export from nucleus; and protein stabilization. Located in perinuclear region of cytoplasm and protein-containing complex. Expressed in several structures, including excretory system; germ line; intestine; nerve ring; and pharynx. Human ortholog(s) of this gene implicated in Alzheimer's disease; autoimmune disease (multiple); and gastrointestinal system cancer (multiple). Is an ortholog of human HSP90AB1 (heat shock protein 90 alpha family class B member 1).