smn-1 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Enables protein self-association. Involved in several processes, including determination of adult lifespan; pharyngeal pumping; and vulval development. Located in nucleus. Expressed in several structures, including body wall musculature; excretory cell; hypodermis; intestine; and vulval muscle. Used to study spinal muscular atrophy. Human ortholog(s) of this gene implicated in spinal muscular atrophy (multiple). Is an ortholog of human SMN1 (survival of motor neuron 1, telomeric) and SMN2 (survival of motor neuron 2, centromeric).