imp-1 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable aspartic endopeptidase activity, intramembrane cleaving. Predicted to be involved in membrane protein proteolysis. Predicted to be located in organelle membrane and plasma membrane. Expressed in neurons. Human ortholog(s) of this gene implicated in primary immunodeficiency disease. Is an ortholog of human SPPL2A (signal peptide peptidase like 2A); SPPL2B (signal peptide peptidase like 2B); and SPPL2C (signal peptide peptidase like 2C).