ubr-1

Caenorhabditis elegans

Enables ubiquitin conjugating enzyme binding activity. Involved in negative regulation of glutamate metabolic process and regulation of backward locomotion. Predicted to be located in cytoplasm. Predicted to be part of ubiquitin ligase complex. Expressed in body wall musculature; lateral ganglion; pharynx; and seam cell. Human ortholog(s) of this gene implicated in Johanson-Blizzard syndrome and atherosclerosis. Is an ortholog of human UBR1 (ubiquitin protein ligase E3 component n-recognin 1) and UBR2 (ubiquitin protein ligase E3 component n-recognin 2).