Enriched in OLL; PVD; hermaphrodite distal tip cell; intestine; and male distal tip cell based on SAGE; microarray; tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including
daf-16;
daf-2; and
skn-1 based on microarray and RNA-seq studies. Is affected by twenty-two chemicals including 1-methylnicotinamide; mianserin; and D-glucose based on RNA-seq and microarray studies. Human ortholog(s) of this gene implicated in atypical Gaucher's disease due to saposin c deficiency; combined saposin deficiency; and late onset Parkinson's disease. Human PSAP enables several functions, including ganglioside binding activity; protein homodimerization activity; and scaffold protein binding activity. Is predicted to encode a protein with the following domains: Saposin-like and Saposin B type domain. Is an ortholog of human PSAP (prosaposin).