tiam-1 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Enables guanyl-nucleotide exchange factor activity. Involved in small GTPase mediated signal transduction. Located in cell periphery and growth cone. Expressed in gonad and neurons. Human ortholog(s) of this gene implicated in neurodevelopmental disorder with language delay and seizures. Is an ortholog of human TIAM2 (TIAM Rac1 associated GEF 2).