fan-1 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable 5'-3' exonuclease activity; 5'-flap endonuclease activity; and flap-structured DNA binding activity. Involved in DNA repair. Located in nucleus. Expressed in embryonic cell; germ cell; head neurons; intestine; and tail neurons. Used to study Fanconi anemia. Human ortholog(s) of this gene implicated in karyomegalic interstitial nephritis. Is an ortholog of human FAN1 (FANCD2 and FANCI associated nuclease 1).