- Klf9 [Search on AGR]
Homo sapiens The protein encoded by this gene is a transcription factor that binds to GC box elements located in the promoter. Binding of the encoded protein to a single GC box inhibits mRNA expression while binding to tandemly repeated GC box elements activates transcription. [provided by RefSeq, Jul 2008]
- GC [Search on AGR]
Drosophila melanogaster gamma-glutamyl carboxylase (GC) encodes an enzyme involved in peptidyl-glutamic acid carboxylation.
- mog-7 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable DNA binding activity. Predicted to be involved in spliceosomal complex disassembly. Predicted to be located in nucleus. Predicted to be part of U2-type post-mRNA release spliceosomal complex. Expressed in germ cell; oocyte; somatic cell; and sperm. Is an ortholog of human GCFC2 (GC-rich sequence DNA-binding factor 2) and PAXBP1 (PAX3 and PAX7 binding protein 1).
- GC [Search on AGR]
Rattus norvegicus Enables vitamin D binding activity. Involved in several processes, including female pregnancy; lactation; and response to estradiol. Located in axon; extracellular space; and perinuclear region of cytoplasm. Biomarker of brain ischemia and hepatocellular carcinoma. Human ortholog(s) of this gene implicated in several diseases, including autoimmune disease (multiple); chronic obstructive pulmonary disease; hepatocellular carcinoma; human immunodeficiency virus infectious disease; and rheumatic fever. Orthologous to human GC (GC vitamin D binding protein); INTERACTS WITH 1-naphthyl isothiocyanate; 2,6-dinitrotoluene; 2-(3,4-dimethoxyphenyl)-5-{[2-(3,4-dimethoxyphenyl)ethyl](methyl)amino}-2-(propan-2-yl)pentanenitrile.
- Slc10a3 [Search on AGR]
Homo sapiens This gene maps to a GC-rich region of the X chromosome and was identified by its proximity to a CpG island. It is thought to be a housekeeping gene. Alternative splicing results in multiple transcript variants encoding distinct isoforms.[provided by RefSeq, Dec 2008]
- Gpbp1l1 [Search on AGR]
Rattus norvegicus Predicted to enable DNA binding activity and RNA binding activity. Predicted to be involved in DNA-templated transcription and positive regulation of DNA-templated transcription. Orthologous to human GPBP1L1 (GC-rich promoter binding protein 1 like 1); INTERACTS WITH 17beta-estradiol; 6-propyl-2-thiouracil; amitrole.
- Gcfc2 [Search on AGR]
Rattus norvegicus Predicted to enable DNA binding activity. Predicted to be involved in spliceosomal complex assembly. Predicted to be located in cytosol; nucleolus; and nucleoplasm. Predicted to be part of U2-type post-mRNA release spliceosomal complex. Orthologous to human GCFC2 (GC-rich sequence DNA-binding factor 2); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; acetamide.
- Klf13 [Search on AGR]
Homo sapiens KLF13 belongs to a family of transcription factors that contain 3 classical zinc finger DNA-binding domains consisting of a zinc atom tetrahedrally coordinated by 2 cysteines and 2 histidines (C2H2 motif). These transcription factors bind to GC-rich sequences and related GT and CACCC boxes (Scohy et al., 2000 [PubMed 11087666]).[supplied by OMIM, Mar 2008]
- Sp6 [Search on AGR]
Homo sapiens SP6 belongs to a family of transcription factors that contain 3 classical zinc finger DNA-binding domains consisting of a zinc atom tetrahedrally coordinated by 2 cysteines and 2 histidines (C2H2 motif). These transcription factors bind to GC-rich sequences and related GT and CACCC boxes (Scohy et al., 2000 [PubMed 11087666]).[supplied by OMIM, Mar 2008]