- dnj-7 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable misfolded protein binding activity; protein kinase inhibitor activity; and protein-folding chaperone binding activity. Involved in PERK-mediated unfolded protein response. Predicted to be located in endoplasmic reticulum lumen. Expressed in head. Is an ortholog of human DNAJC3 (DnaJ heat shock protein family (Hsp40) member C3).
- erd-2.2 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable ER retention sequence binding activity. Predicted to be involved in protein retention in ER lumen; protein transport; and vesicle-mediated transport. Predicted to be located in endoplasmic reticulum membrane. Human ortholog(s) of this gene implicated in osteogenesis imperfecta type 21. Is an ortholog of human KDELR2 (KDEL endoplasmic reticulum protein retention receptor 2).