- barr [Search on AGR]
Drosophila melanogaster barren (barr) encodes a chromatin binding protein involved in chromatin condensation. It regulates Malpighian tubule development and epithelial morphogenesis.
- Lrif1 [Search on AGR]
Homo sapiens Predicted to enable retinoic acid receptor binding activity. Involved in dosage compensation by inactivation of X chromosome. Located in Barr body; centriolar satellite; and nucleoplasm. Colocalizes with chromosome, telomeric region. [provided by Alliance of Genome Resources, Apr 2022]
- ZK686.3 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to be involved in protein N-linked glycosylation via asparagine. Predicted to be located in endoplasmic reticulum membrane. Predicted to be part of oligosaccharyltransferase complex. Used to study bacterial infectious disease. Human ortholog(s) of this gene implicated in X-linked immunodeficiency with magnesium defect, Epstein-Barr virus infection, and neoplasia; autosomal recessive intellectual developmental disorder 7; and congenital disorder of glycosylation Icc. Is an ortholog of human MAGT1 (magnesium transporter 1) and TUSC3 (tumor suppressor candidate 3).
- Cap-D2 [Search on AGR]
Drosophila melanogaster CAP-D2 condensin subunit (Cap-D2) encodes a component of the conserved condensin I complex, together with the products of Cap-G, barr, SMC2 and glu. Condensin I associates with mitotic chromatin and plays a crucial role in shaping mitotic chromosomes and in their faithful segregation during anaphase.
- Ebi3 [Search on AGR]
Rattus norvegicus Predicted to enable cytokine receptor activity and interleukin-27 receptor binding activity. Predicted to be involved in T cell proliferation. Biomarker of pre-eclampsia. Orthologous to human EBI3 (Epstein-Barr virus induced 3); PARTICIPATES IN interleukin-27 signaling pathway; INTERACTS WITH 17beta-estradiol; 17beta-estradiol 3-benzoate; 2,3,7,8-tetrachlorodibenzodioxine.
- Cr2 [Search on AGR]
Homo sapiens This gene encodes a membrane protein, which functions as a receptor for Epstein-Barr virus (EBV) binding on B and T lymphocytes. Genetic variations in this gene are associated with susceptibility to systemic lupus erythematosus type 9 (SLEB9). Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Sep 2009]
- Lrif1 [Search on AGR]
Rattus norvegicus Predicted to enable nuclear retinoic acid receptor binding activity. Predicted to be involved in dosage compensation by inactivation of X chromosome. Predicted to be located in Barr body; centriolar satellite; and nucleoplasm. Predicted to colocalize with chromosome, telomeric region. Human ortholog(s) of this gene implicated in facioscapulohumeral muscular dystrophy. Orthologous to human LRIF1 (ligand dependent nuclear receptor interacting factor 1); INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil.
- Ebi3 [Search on AGR]
Homo sapiens This gene was identified by its induced expression in B lymphocytes in response Epstein-Barr virus infection. It encodes a secreted glycoprotein belonging to the hematopoietin receptor family, and heterodimerizes with a 28 kDa protein to form interleukin 27 (IL-27). IL-27 regulates T cell and inflammatory responses, in part by activating the Jak/STAT pathway of CD4+ T cells. [provided by RefSeq, Sep 2008]
- Ncaph [Search on AGR]
Homo sapiens This gene encodes a member of the barr gene family and a regulatory subunit of the condensin complex. This complex is required for the conversion of interphase chromatin into condensed chromosomes. The protein encoded by this gene is associated with mitotic chromosomes, except during the early phase of chromosome condensation. During interphase, the protein has a distinct punctate nucleolar localization. Alternatively spliced transcript variants encoding different proteins have been described. [provided by RefSeq, Jul 2013]