unc-44 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Enables cell adhesion molecule binding activity. Involved in several processes, including axon guidance; establishment or maintenance of cytoskeleton polarity; and regulation of cellular component organization. Located in lateral plasma membrane. Expressed in hermaphrodite gonad; hypodermis; intestinal cell; and vulval cell. Human ortholog(s) of this gene implicated in several diseases, including ankyrin-B-related cardiac arrhythmia; autosomal recessive intellectual developmental disorder 37; and heart conduction disease (multiple). Is an ortholog of human ANK2 (ankyrin 2) and ANK3 (ankyrin 3).