Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in canonical Wnt signaling pathway. Expressed in head neurons and intestine. Is an ortholog of human SP5 (Sp5 transcription factor).
Is predicted to encode a protein with the following domains: Zinc finger, C2H2 type; Zinc finger C2H2 superfamily; and Zinc finger C2H2-type. Is an ortholog of C. elegans sptf-2. In C. elegans, sptf-2 is involved in canonical Wnt signaling pathway.
Is predicted to encode a protein with the following domains: Zinc finger, C2H2 type; Zinc finger C2H2 superfamily; and Zinc finger C2H2-type. Is an ortholog of C. elegans sptf-2. In C. elegans, sptf-2 is involved in canonical Wnt signaling pathway.
Is predicted to encode a protein with the following domains: Zinc finger, C2H2 type; Zinc finger C2H2 superfamily; and Zinc finger C2H2-type. Is an ortholog of C. elegans sptf-2. In C. elegans, sptf-2 is involved in canonical Wnt signaling pathway.
Is predicted to encode a protein with the following domains: Zinc finger, C2H2 type; Zinc finger C2H2 superfamily; and Zinc finger C2H2-type. Is an ortholog of C. elegans sptf-2. In C. elegans, sptf-2 is involved in canonical Wnt signaling pathway.
Is predicted to encode a protein with the following domains: Zinc finger, C2H2 type; Zinc finger C2H2 superfamily; and Zinc finger C2H2-type. Is an ortholog of C. elegans sptf-2 and sptf-3. In C. elegans, sptf-2 is involved in canonical Wnt signaling pathway.
Is predicted to encode a protein with the following domains: Zinc finger, C2H2 type; Zinc finger C2H2 superfamily; and Zinc finger C2H2-type. Is an ortholog of C. elegans sptf-2 and sptf-3. In C. elegans, sptf-2 is involved in canonical Wnt signaling pathway.
Is predicted to encode a protein with the following domain: Zinc finger C2H2 superfamily. Is an ortholog of C. elegans sptf-1 and sptf-2. In C. elegans, sptf-1 is involved in neuron differentiation and positive regulation of gene expression.
Enables DNA-binding transcription factor activity, RNA polymerase II-specific and chromatin binding activity. Involved in several processes, including generation of neurons; nematode larval development; and positive regulation of transcription by RNA polymerase II. Located in nucleus. Expressed in several structures, including MSpaa; hypodermal cell; intestine; pharyngeal cell; and somatic nervous system. Human ortholog(s) of this gene implicated in congenital heart disease and dilated cardiomyopathy. Is an ortholog of human SP1 (Sp1 transcription factor); SP3 (Sp3 transcription factor); and SP4 (Sp4 transcription factor).