Predicted to enable D-erythro-sphingosine kinase activity and acetyltransferase activity. Involved in mitochondrial unfolded protein response; positive regulation of acetylcholine secretion, neurotransmission; and regulation of locomotion. Located in several cellular components, including mitochondrion; neuronal cell body; and presynaptic periactive zone. Expressed in several structures, including body wall musculature; excretory canal; intestine; linker cell; and neurons. Human ortholog(s) of this gene implicated in type 2 diabetes mellitus. Is an ortholog of human SPHK1 (sphingosine kinase 1) and SPHK2 (sphingosine kinase 2).
Predicted to enable kinase activity. Is an ortholog of C. elegans sphk-1. In C. elegans, sphk-1 is involved in mitochondrial unfolded protein response; positive regulation of acetylcholine secretion, neurotransmission; and regulation of locomotion.
Predicted to enable kinase activity. Is an ortholog of C. elegans sphk-1. In C. elegans, sphk-1 is involved in mitochondrial unfolded protein response; positive regulation of acetylcholine secretion, neurotransmission; and regulation of locomotion.
Predicted to enable kinase activity. Is an ortholog of C. elegans sphk-1. In C. elegans, sphk-1 is involved in mitochondrial unfolded protein response; positive regulation of acetylcholine secretion, neurotransmission; and regulation of locomotion.
Predicted to enable kinase activity. Is an ortholog of C. elegans sphk-1. In C. elegans, sphk-1 is involved in mitochondrial unfolded protein response; positive regulation of acetylcholine secretion, neurotransmission; and regulation of locomotion.
Predicted to enable kinase activity. Is an ortholog of C. elegans sphk-1. In C. elegans, sphk-1 is involved in mitochondrial unfolded protein response; positive regulation of acetylcholine secretion, neurotransmission; and regulation of locomotion.
Predicted to enable kinase activity. Is an ortholog of C. elegans sphk-1. In C. elegans, sphk-1 is involved in mitochondrial unfolded protein response; positive regulation of acetylcholine secretion, neurotransmission; and regulation of locomotion.
Predicted to enable kinase activity. Is an ortholog of C. elegans sphk-1. In C. elegans, sphk-1 is involved in mitochondrial unfolded protein response; positive regulation of acetylcholine secretion, neurotransmission; and regulation of locomotion.
Predicted to enable kinase activity. Is an ortholog of C. elegans sphk-1. In C. elegans, sphk-1 is involved in mitochondrial unfolded protein response; positive regulation of acetylcholine secretion, neurotransmission; and regulation of locomotion.