Predicted to enable damaged DNA binding activity and single-stranded DNA binding activity. Predicted to be involved in double-strand break repair via homologous recombination. Located in condensed nuclear chromosome and nucleoplasm. Is an ortholog of human SMC6 (structural maintenance of chromosomes 6).
Predicted to enable ATP binding activity and ATP hydrolysis activity. Predicted to be involved in chromosome organization and double-strand break repair. Predicted to be located in chromosome. Is an ortholog of C. elegans smc-6.
Enables ubiquitin protein ligase binding activity. Involved in several processes, including cellular senescence; positive regulation of chromosome segregation; and telomere maintenance via recombination. Located in chromosome and nuclear body. Part of Smc5-Smc6 complex. [provided by Alliance of Genome Resources, Apr 2022]
Is predicted to encode a protein with the following domains: Structural maintenance of chromosomes protein 6 and P-loop containing nucleoside triphosphate hydrolase. Is an ortholog of C. elegans C23H4.6 and smc-6.