Enables calcium-activated potassium channel activity and outward rectifier potassium channel activity. Involved in positive regulation of neurotransmitter secretion and potassium ion transport. Located in axon. Expressed in amphid neurons; body wall musculature; motor neurons; nerve ring; and vulval muscle. Human ortholog(s) of this gene implicated in autosomal dominant nocturnal frontal lobe epilepsy 5; developmental and epileptic encephalopathy 14; and developmental and epileptic encephalopathy 57. Is an ortholog of human KCNT1 (potassium sodium-activated channel subfamily T member 1) and KCNT2 (potassium sodium-activated channel subfamily T member 2).
Enables calcium-activated potassium channel activity and voltage-gated potassium channel activity. Involved in several processes, including behavioral response to ethanol; pharyngeal pumping; and sarcomere organization. Located in M band; striated muscle dense body; and synapse. Expressed in several structures, including AWC; body wall musculature; non-striated muscle; pharyngeal neurons; and somatic nervous system. Used to study Duchenne muscular dystrophy and alcohol use disorder. Human ortholog(s) of this gene implicated in Alzheimer's disease; idiopathic generalized epilepsy; paroxysmal nonkinesigenic dyskinesia 3; and spermatogenic failure. Is an ortholog of human KCNMA1 (potassium calcium-activated channel subfamily M alpha 1).
Enables transmembrane transporter binding activity. Located in neuron projection and striated muscle dense body. Expressed in body wall musculature; head mesodermal cell; muscle cell; neurons; and somatic nervous system.
Predicted to be involved in potassium ion transport. Predicted to be located in membrane. Is an ortholog of C. elegans slo-2. In C. elegans, slo-2 is involved in positive regulation of neurotransmitter secretion and potassium ion transport.
Predicted to be involved in potassium ion transport. Predicted to be located in membrane. Is an ortholog of C. elegans slo-2. In C. elegans, slo-2 is involved in positive regulation of neurotransmitter secretion and potassium ion transport.
Predicted to be involved in potassium ion transport. Predicted to be located in membrane. Is an ortholog of C. elegans slo-2. In C. elegans, slo-2 is involved in positive regulation of neurotransmitter secretion and potassium ion transport.
Predicted to be involved in potassium ion transport. Predicted to be located in membrane. Is an ortholog of C. elegans slo-2. In C. elegans, slo-2 is involved in positive regulation of neurotransmitter secretion and potassium ion transport.
Predicted to be involved in potassium ion transport. Predicted to be located in membrane. Is an ortholog of C. elegans slo-2. In C. elegans, slo-2 is involved in positive regulation of neurotransmitter secretion and potassium ion transport.