Enables cysteine-type deubiquitinase activity and ionotropic glutamate receptor binding activity. Involved in anterior/posterior axis specification, embryo; positive regulation of gene expression; and positive regulation of locomotion involved in locomotory behavior. Located in endosome and neuronal cell body. Expressed in body wall musculature; intestine; nervous system; pharynx; and vulval muscle. Is an ortholog of human USP46 (ubiquitin specific peptidase 46).
Predicted to enable cysteine-type deubiquitinase activity and proteasome binding activity. Predicted to be involved in regulation of proteasomal protein catabolic process. Predicted to be part of proteasome complex. Is an ortholog of human USP14 (ubiquitin specific peptidase 14).
Predicted to enable K48-linked deubiquitinase activity and cysteine-type carboxypeptidase activity. Predicted to be involved in proteolysis. Is an ortholog of human MINDY1 (MINDY lysine 48 deubiquitinase 1) and MINDY2 (MINDY lysine 48 deubiquitinase 2).
Involved in miRNA-mediated gene silencing by inhibition of translation and positive regulation of development, heterochronic. Expressed in P5.p hermaphrodite; P7.p hermaphrodite; RID; and seam cell. Used to study Parkinson's disease.
Predicted to enable DNA binding activity. Involved in innate immune response. Predicted to be located in chromosome and nucleus. Predicted to be part of nucleosome. Expressed in gonad. Is an ortholog of several human genes including H2BC3 (H2B clustered histone 3); H2BC5 (H2B clustered histone 5); and H2BC8 (H2B clustered histone 8).
Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in anatomical structure morphogenesis and response to salt stress. Located in nucleus. Expressed in ciliated neurons; interfacial epithelial cell; intestine; labial sensillum; and tail. Human ortholog(s) of this gene implicated in posterior polymorphous corneal dystrophy 1. Is an ortholog of human OVOL1 (ovo like transcriptional repressor 1) and OVOL2 (ovo like zinc finger 2).