Enables nicotinamidase activity. Involved in nicotinamide metabolic process. Located in cytoplasm; extracellular space; and nucleus. Expressed in several structures, including coelomocyte; epithelial cell; head ganglion; lumbar neurons; and pharyngeal cell.
Predicted to enable RNA polymerase II CTD heptapeptide repeat phosphatase activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Human ortholog(s) of this gene implicated in several diseases, including carcinoma (multiple); endometrial cancer; and primary autosomal recessive microcephaly 1. Is an ortholog of human MCPH1 (microcephalin 1).