Predicted to enable GTP binding activity; GTPase activity; and translation elongation factor activity. Predicted to be involved in translational elongation. Human ortholog(s) of this gene implicated in Alzheimer's disease; autosomal dominant intellectual developmental disorder 38; developmental and epileptic encephalopathy 33; and ovarian cancer. Is an ortholog of human EEF1A1 (eukaryotic translation elongation factor 1 alpha 1); EEF1A1P5 (eukaryotic translation elongation factor 1 alpha 1 pseudogene 5); and EEF1A2 (eukaryotic translation elongation factor 1 alpha 2).
Enables GTPase activity. Predicted to be involved in translational elongation. Predicted to be located in cytoplasm. Expressed in hypodermis; intestine; muscle cell; and neurons. Human ortholog(s) of this gene implicated in Alzheimer's disease; autosomal dominant intellectual developmental disorder 38; developmental and epileptic encephalopathy 33; and ovarian cancer. Is an ortholog of human EEF1A1 (eukaryotic translation elongation factor 1 alpha 1); EEF1A1P5 (eukaryotic translation elongation factor 1 alpha 1 pseudogene 5); and EEF1A2 (eukaryotic translation elongation factor 1 alpha 2).
Predicted to enable GTPase activity; ribosome binding activity; and translation elongation factor activity. Involved in defense response to Gram-negative bacterium and negative regulation of gene expression. Predicted to be located in cytosol. Predicted to be part of ribonucleoprotein complex. Expressed in several structures, including germ line. Human ortholog(s) of this gene implicated in several diseases, including Alzheimer's disease; brain glioblastoma multiforme; carcinoma (multiple); and spinocerebellar ataxia type 26. Is an ortholog of human EEF2 (eukaryotic translation elongation factor 2).