Enables protease binding activity and protein homodimerization activity. Involved in apoptotic process; determination of adult lifespan; and regulation of cell cycle. Located in mitochondrial outer membrane and protein-containing complex. Expressed in body wall musculature; intestine; pharynx; and vulval muscle. Human ortholog(s) of this gene implicated in ductal carcinoma in situ and perinatal necrotizing enterocolitis. Is an ortholog of human BNIP3 (BCL2 interacting protein 3).
Predicted to enable oxidoreductase activity. Human ortholog(s) of this gene implicated in several diseases, including ocular albinism 1; oculocutaneous albinism (multiple); and vitiligo. Is an ortholog of human DCT (dopachrome tautomerase); TYR (tyrosinase); and TYRP1 (tyrosinase related protein 1).
Predicted to enable metal ion binding activity and monooxygenase activity. Expressed in head mesodermal cell. Human ortholog(s) of this gene implicated in several diseases, including ocular albinism 1; oculocutaneous albinism (multiple); and vitiligo. Is an ortholog of human DCT (dopachrome tautomerase) and TYR (tyrosinase).