- atp-3 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to contribute to proton-transporting ATP synthase activity, rotational mechanism. Involved in determination of adult lifespan and proton motive force-driven mitochondrial ATP synthesis. Predicted to be located in mitochondrial inner membrane. Predicted to be part of mitochondrial proton-transporting ATP synthase, stator stalk and proton-transporting ATP synthase complex, catalytic core F(1). Human ortholog(s) of this gene implicated in Alzheimer's disease; clear cell renal cell carcinoma; and mitochondrial complex V (ATP synthase) deficiency nuclear type 7. Is an ortholog of human ATP5PO (ATP synthase peripheral stalk subunit OSCP).
- ZC262.5 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable proton-transporting ATP synthase activity, rotational mechanism. Predicted to be involved in proton motive force-driven ATP synthesis. Predicted to be part of mitochondrial proton-transporting ATP synthase complex, catalytic sector F(1). Human ortholog(s) of this gene implicated in mitochondrial complex V (ATP synthase) deficiency nuclear type 3. Is an ortholog of human ATP5F1E (ATP synthase F1 subunit epsilon) and ATP5F1EP2 (ATP synthase F1 subunit epsilon pseudogene 2).
- hpo-18 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to contribute to proton-transporting ATP synthase activity, rotational mechanism. Predicted to be involved in proton motive force-driven mitochondrial ATP synthesis. Predicted to be located in mitochondrial inner membrane. Predicted to be part of mitochondrial proton-transporting ATP synthase complex, catalytic sector F(1). Human ortholog(s) of this gene implicated in mitochondrial complex V (ATP synthase) deficiency nuclear type 3. Is an ortholog of human ATP5F1E (ATP synthase F1 subunit epsilon) and ATP5F1EP2 (ATP synthase F1 subunit epsilon pseudogene 2).
- Y54E2A.4 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable several functions, including ATP binding activity; ATP hydrolysis activity; and helicase activity. Predicted to be involved in gene expression and nucleic acid metabolic process. Is an ortholog of human ASCC3 (activating signal cointegrator 1 complex subunit 3).
- R05D3.6 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to contribute to proton-transporting ATP synthase activity, rotational mechanism. Predicted to be involved in proton motive force-driven mitochondrial ATP synthesis. Located in mitochondrion. Human ortholog(s) of this gene implicated in mitochondrial complex V (ATP synthase) deficiency nuclear type 3. Is an ortholog of human ATP5F1E (ATP synthase F1 subunit epsilon) and ATP5F1EP2 (ATP synthase F1 subunit epsilon pseudogene 2).
- atad-3 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable ATP binding activity and ATP hydrolysis activity. Involved in mitochondrion organization. Located in mitochondrion. Is an ortholog of human ATAD3A (ATPase family AAA domain containing 3A) and ATAD3B (ATPase family AAA domain containing 3B).
- Y73B6BL.14 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable ATP binding activity; DNA binding activity; and DNA ligase (ATP) activity. Predicted to be involved in DNA recombination; DNA repair; and DNA replication. Human ortholog(s) of this gene implicated in mitochondrial DNA depletion syndrome 20 and pancreatic cancer. Is an ortholog of human LIG3 (DNA ligase 3).
- pgp-3 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable ATPase-coupled transmembrane transporter activity and efflux transmembrane transporter activity. Involved in defense response to Gram-negative bacterium; innate immune response; and stress response to cadmium ion. Located in apical plasma membrane. Expressed in excretory canal; excretory cell; intestinal cell; intestine; and pharynx. Human ortholog(s) of this gene implicated in several diseases, including autoimmune disease (multiple); carcinoma (multiple); and intrahepatic cholestasis (multiple). Is an ortholog of several human genes including ABCB1 (ATP binding cassette subfamily B member 1); ABCB11 (ATP binding cassette subfamily B member 11); and ABCB4 (ATP binding cassette subfamily B member 4).