- WBPaper00032430:rheb-1_regulated
Statistical analysis was performed by one-way analysis of variance (ANOVA) with a Benjamini and Hochberg false discovery rate (BH-FDR 5 0.1) multiple testing correction followed by Tukey post-hoc tests using log-transformed data (GeneSpring). Three-thousand-and-thirty-one probe sets were identified to be regulated by fasting in control RNAi-treated worms. We defined RHEB-1-dependent or TOR-dependent genes as those in which the expression level induced by fasting was reduced to less than half under rheb-1 RNAi or TOR (let-363) RNAi conditions.
Fasting-induced upregulated genes whose induction is suppressed by rheb-1 RNAi.
- WBPaper00044501:gld-1_let-7_regulated
N.A.
Proteins that showed differential expression in (B) let-7(mg279);[let-7 sponge] when comparing to (A) [let-7 sponge], and in (C) gld-1(op236); let-7(mg279);[let-7 sponge] when comparing to (A) [let-7 sponge]
- WBPaper00050163:let-418(RNAi)_upregulated_24-cell-embryo
DESeq and EdgeR were used. A threshold of 1.5 log2 fold change and a p value <10 % were applied. let-418: wild-type; let-418(RNAi)-treated embryos; chd-3: chd-3(eh4);controlGFP(RNAi)-treated embryos; chd-3_let-418: chd-3(eh4); let-418(RNAi)-treated embryos. All fold changes are calculated versus wild-type;control(RNAi)-treated embryos. 1h and 3h correspond to the 24- and 100-cell stages, respectively.
Transcripts that showed significantly increased expression in 24-cell stage embryo of let-418(RNAi) animals, comparing to in control RNAi (with gfp control vector) animals.
- WBPaper00050163:chd-3(eh4)\;let-418(RNAi)_downregulated_24-cell-embryo
DESeq and EdgeR were used. A threshold of 1.5 log2 fold change and a p value <10 % were applied. let-418: wild-type; let-418(RNAi)-treated embryos; chd-3: chd-3(eh4);controlGFP(RNAi)-treated embryos; chd-3_let-418: chd-3(eh4); let-418(RNAi)-treated embryos. All fold changes are calculated versus wild-type;control(RNAi)-treated embryos. 1h and 3h correspond to the 24- and 100-cell stages, respectively.
Transcripts that showed significantly decreased expression in 24-cell stage embryo of chd-3(eh4)let-418(RNAi) animals, comparing to in N2 animals injected with gfp control RNAi vector.
- WBPaper00050163:let-418(RNAi)_downregulated_24-cell-embryo
DESeq and EdgeR were used. A threshold of 1.5 log2 fold change and a p value <10 % were applied. let-418: wild-type; let-418(RNAi)-treated embryos; chd-3: chd-3(eh4);controlGFP(RNAi)-treated embryos; chd-3_let-418: chd-3(eh4); let-418(RNAi)-treated embryos. All fold changes are calculated versus wild-type;control(RNAi)-treated embryos. 1h and 3h correspond to the 24- and 100-cell stages, respectively.
Transcripts that showed significantly decreased expression in 24-cell stage embryo of let-418(RNAi) animals, comparing to in control RNAi (with gfp control vector) animals.
- WBPaper00050163:let-418(RNAi)_upregulated_100-cell-embryo
DESeq and EdgeR were used. A threshold of 1.5 log2 fold change and a p value <10 % were applied. let-418: wild-type; let-418(RNAi)-treated embryos; chd-3: chd-3(eh4);controlGFP(RNAi)-treated embryos; chd-3_let-418: chd-3(eh4); let-418(RNAi)-treated embryos. All fold changes are calculated versus wild-type;control(RNAi)-treated embryos. 1h and 3h correspond to the 24- and 100-cell stages, respectively.
Transcripts that showed significantly increased expression in 100-cell stage embryo of let-418(RNAi) animals, comparing to in control RNAi (with gfp control vector) animals.