- WBPaper00061613:human-amyloid-beta_upregulated
edgeR p-value < 0.01 and fold change > 4.
Transcripts that showed significantly increased expression in animals with pan-neuronal expression of human amyloid beta (snb-1p-Amyloid-beta(1-42) + mtl-2p-GFP), comparing to in N2 animals.
- WBPaper00061613:human-amyloid-beta_downregulated
edgeR p-value < 0.01 and fold change > 4.
Transcripts that showed significantly decreased expression in animals with pan-neuronal expression of human amyloid beta (snb-1p-Amyloid-beta(1-42) + mtl-2p-GFP), comparing to in N2 animals.
- WBPaper00061613:human-amyloid-beta_alpha-Synuclein(A53T)_downregulated
edgeR p-value < 0.01 and fold change > 4.
Transcripts that showed significantly decreased expression in animals with pan-neuronal expression of both human amyloid beta (snb-1p-Amyloid-beta(1-42) + mtl-2p-GFP) and human alpha-Synuclein(A53T) (aex-3p-alpha-syn (A53T)), comparing to in N2 animals.
- WBPaper00061613:human-amyloid-beta_alpha-Synuclein(A53T)_upregulated
edgeR p-value < 0.01 and fold change > 4.
Transcripts that showed significantly increased expression in animals with pan-neuronal expression of both human amyloid beta (snb-1p-Amyloid-beta(1-42) + mtl-2p-GFP) and human alpha-Synuclein(A53T) (aex-3p-alpha-syn (A53T)), comparing to in N2 animals.
- WBPaper00004966:beta-Naphthoflavone_induced
Differentially Expressed C. elegans CYP Genes Induced by beta-Naphthoflavone. Differential hybridization was performed using mRNA samples isolated from beta-naphthoflavone- and DMSO-treated worm populations, respectively.
- WBPaper00053154:human-amyloid-beta_tau_regulated
To identify differential gene expression, analysis was performed using CuffLinks 2.2.1 with false discovery rate corrected P values (q values) of < 0.05 and log2 (fold change) > 1 or < 1.
Transcripts that showed differential expression between N2 and animals expressing human amyloid beta peptide (strain CL2355) and pro-aggregating tau (strain BR5270) or anti-aggregating tau protein (BR5271), at L4 larva stage.
- WBPaper00061210:huIs179_downregulated
Differential gene expression analysis was done with DESeq2 R-package using an FDR based on adjusted P < 0.05. (The threshold was reset from FDR < 0.1 to FDR < 0.05 by WormBase curator.)
Transcripts that showed significantly decreased expression in Q neuroblast descendant cells expressing a constitutively active, N terminally truncated form of BAR-1 (beta-catenin) (del-N-BAR-1 Q) (huIs179).
- WBPaper00061210:huIs179_upregulated
Differential gene expression analysis was done with DESeq2 R-package using an FDR based on adjusted P < 0.05. (The threshold was reset from FDR < 0.1 to FDR < 0.05 by WormBase curator.)
Transcripts that showed significantly increased expression in Q neuroblast descendant cells expressing a constitutively active, N terminally truncated form of BAR-1 (beta-catenin) (del-N-BAR-1 Q) (huIs179).
- WBPaper00026720:AmyloidBeta_oxidized
Statistical comparison of carbonyl levels of proteins, matched with anti-DNP positive spots on 2D-oxyblots from C. elegans expressing amyloid beta (142) and control C. elegans samples, were performed using both ANOVA, and Students t-tests.
Proteins that were increasingly carbonylated by human amyloid beata (1-42) (CL4176) comparing to in control worm (CL1234), according to 2D-PAGE and Mass Spec analysis.
- WBPaper00064130:Beta-Amyloid_24h_downregulated_mRNA
A 2-fold change in expression level and a false discovery rate analog of p < 0.05.
Transcripts that showed significantly decreased expression after 24 hours of induction of human beta Amyloid at young adult stage