- WBPaper00030839:Larval_A_Class
A two-class unpaired analysis of the data was performed to identify genes that differ by >= 1.5-fold from the reference at a FDR of <1% for the larval pan-neural, embryonic pan-neural, and larval A-class motor neuron datasets.
Larval A-class motor neuron enriched genes.
- WBPaper00030839:Embryo_A_Class
A two-class unpaired analysis of the data was performed to identify genes that differ by >= 1.5-fold from the reference at a FDR of <1% for the larval pan-neural, embryonic pan-neural, and larval A-class motor neuron datasets.
Embryonic A-class motor neuron enriched genes.
- WBPaper00032454:IR_upregulated
To identify differentially expressed genes, gene expression intensity was compared using a moderated t-test and a Bayes smoothing approach developed for a low number of replicates.
Genes up-regulated following ionizing radiation (IR) treatment.
- WBPaper00055226:ADR-2_target_N2
DESeq2, p-value < 0.05 and a fold enrichment log2fold > 0.5.
Genes that exhibit a differential enrichment (p-value < 0.05 and a fold enrichment (log2fold)> 0.5) between the ADR-2 IPs from N2 and adr-2(ok735)worms.
- WBPaper00036464:S.aureus-RN6390_regulated
The two conditions were then compared in Resolver to determine fold change for each probe set and a p-value, using a modified t test. Genes with a 2-fold or greater fold change and a p-value ,0.01 were considered differentially expressed.
Genes with altered expression after 8 h S. aureus infection.
- WBPaper00055226:ADR-2_target_adr-1(tm668)
DESeq2, p-value < 0.05 and a fold enrichment log2fold > 0.5.
Genes that exhibit a differential enrichment (p-value < 0.05 and a fold enrichment (log2fold)> 0.5) between the ADR-2 IPs from adr-1(tm668) worms and adr-2(ok735) worm.
- WBPaper00044316:HgCl2_20uM_downregulated
Rosetta Resolver was used to identify differentially expressed genes using an error-weighted, 1-way ANOVA with a Bonferroni correction. A 2-fold change in expression, relative to untreated controls, and a p-value < 0.01 was required for a gene to qualify as significantly, differentially expressed.
Genes that showed decreased expression after exposure to 20uM HgCl2 for 24 hours.
- WBPaper00044316:CH3HgCl_7.5uM_downregulated
Rosetta Resolver was used to identify differentially expressed genes using an error-weighted, 1-way ANOVA with a Bonferroni correction. A 2-fold change in expression, relative to untreated controls, and a p-value < 0.01 was required for a gene to qualify as significantly, differentially expressed.
Genes that showed decreased expression after exposure to 7.5uM CH3HgCl for 24 hours.
- WBPaper00044316:CH3HgCl_7.5uM_upregulated
Rosetta Resolver was used to identify differentially expressed genes using an error-weighted, 1-way ANOVA with a Bonferroni correction. A 2-fold change in expression, relative to untreated controls, and a p-value < 0.01 was required for a gene to qualify as significantly, differentially expressed.
Genes that showed increased expression after exposure to 7.5uM CH3HgCl for 24 hours.