- WBPaper00061390:daf-22(ok693)_ascarosides_upregulated
DESeq fold change > 2, p < 0.001.
Transcripts that showed significantly increased expression after daf-22(ok693) L1 larva animals were exposed to 150uL of an ascaroside cocktail made of equal amounts (50uL) of 33uM synthetic ascr#2, ascr#3, and ascr#8 in ethanol, comparing to control animals exposed to 150uL EtOH.
- WBPaper00061390:daf-22(ok693)_ascarosides_downregulated
DESeq fold change > 2, p < 0.001.
Transcripts that showed significantly decreased expression after daf-22(ok693) L1 larva animals were exposed to 150uL of an ascaroside cocktail made of equal amounts (50uL) of 33uM synthetic ascr#2, ascr#3, and ascr#8 in ethanol, comparing to control animals exposed to 150uL EtOH.
- WBPaper00047070:DAF-16-dependent_UV_response
Differentially expressed genes were determined by ANOVA analysis using the Partek software package.
DAF-16-dependent genes as being significantly induced (FC > 1.5; P < 0.01) following UV treatment in daf-2 mutants and more strongly induced following UV treatment in daf-2 versus daf-2;daf-16, daf-2 versus N2, and N2 versus daf-16.
- WBPaper00031040:TGF-beta_adult_downregulated
SAM
TGF- Dauer pathway adult transcriptional targets. Results obtained by comparing the microarray results of the dauer-constitutive mutants daf-7(e1372), daf-7(m62), and daf-1(m40) with dauer-defective mutants daf-3(mgDf90), daf-5(e1386), and daf-7(e1372);daf-3(mgDf90) double mutants at the permissive temperature, 20C, on the first day of adulthood.
- WBPaper00031040:TGF-beta_adult_upregulated
SAM
TGF- Dauer pathway adult transcriptional targets. Results obtained by comparing the microarray results of the dauer-constitutive mutants daf-7(e1372), daf-7(m62), and daf-1(m40) with dauer-defective mutants daf-3(mgDf90), daf-5(e1386), and daf-7(e1372);daf-3(mgDf90) double mutants at the permissive temperature, 20C, on the first day of adulthood.
- [cgc5976]:class_1
hierarchical clustering
The cluster contains genes that are upregulated with daf-2 RNAi treatment and in daf-2 pathway mutants, and downregulated with daf-16 RNAi treatment.
- [cgc5976]:class_2
hierarchical clustering
The cluster contains genes that are upregulated with daf-16 RNAi treatment and downregulated with daf-2 RNAi treatment and in daf-2 pathway mutants.
- WBPaper00035479:daf-16(RNAi)_downregulated
Significance Analysis of Microarray (SAM) was performed to identify genes that were differentially regulated in each of the comparisons.For DAF-16 regulated genes, 1% median false positive discovery rate was used.
Genes upregulated in daf-2(-) compared to daf-16(-); daf-2(-)
- WBPaper00035479:daf-16(RNAi)_upregulated
Significance Analysis of Microarray (SAM) was performed to identify genes that were differentially regulated in each of the comparisons.For DAF-16 regulated genes, 1% median false positive discovery rate was used.
Genes downregulated in daf-2(-) compared to daf-16(-); daf-2(-)